Deliverables

WP1 - Fundamental concepts and definitions

D1.1 Mythological and artistic representations of chimeras and hybrids

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D1.2 Identification and discussion of conceptual uncertainties relating to organoids, chimeric entities, and hybrids

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D1.3 The challenging history of organoid research and its implications for ontology and ethics

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D1.4 Typology for artificial biological entities

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WP2 - Mapping Organoids and HTA for organoids

D2.1 The research landscape of organoid and organ-on-a-chip models

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D2.2 A traditional health technology assessment of organoids and organ-on-chips

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D2.3 Adaptation of health technology assessment -HTA- to evaluate organoids and organ-on-a-chip as emerging technologies in the clinic

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D2.4 An amended health technology assessment (HTA) to evaluate organdies as emerging technologies in the clinic

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WP3 - Map and compare normative, RE and RI frameworks

D3.1 Map report of Normative, Research Ethics and Research Integrity frameworks

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D3.2 Comparative analysis

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WP4 - Co-creation and validation

D4.1 Protocol

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D4.2 Report on Participant Selection and Procedures and Criteria for Recruitment

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D4.3 Public attitudes, understandings and perspectives on organoid research

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D4.4 Report on the expert interviews and co-creation workshops

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D4.5 Report on Focus Group Consultation concerning an Ethical and Legal Framework for Organoid-based Technologies

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WP5 - Building operational guidelines

D5.1_Operational guidelines_Final Interactive Version

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D5.2_Code_of_responsible-conduct_Final

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D5.3_Amendment ECoC_Final

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WP6 - Contributions to existing Ethics and Normative frameworks

D6.1 Regulating organoid and organoid-related activities: An analysis of the regulatory gaps and areas of over-regulation

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D6.2 Regulating organoid and organoid-related activities: Proposals to address regulatory gaps and areas of over-regulation

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WP8 - Dissemination, communication and exploitation

D8.1 Dissemination and communication plan

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D8.2 Newsletters and leaflets

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D8.4 1st Policy brief

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D8.6 2nd Policy brief

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